PATHOLOGY
Cells Prove to Have Strong Response To Their Physical Environment
Force of Extracellular Matrix Pushes Cells Toward Death or Division
Cells live in a rough and tumble world. Not only are they subject to the onslaughts of hormones and growth factors, cells are tugged, squeezed, and splayed by the dense matrix of fibers and proteins that surround them. Twenty years ago, Donald Ingber had the heretical idea that mechanical forces exerted by the extracellular matrix had as much to do with telling a cell whether to grow and divide as the commands issued by growth factors. But for years it remained an idea in search of experimental evidence.
FULL STORY
BIOLOGICAL CHEMISTRY
The Ins and Outs of Making a Ribosome
EDUCATION
Introducing the Class Of 2003
