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Molecular Biology:
Matrix-buster Inhibitor Has Second Way to Throttle Angiogenesis
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Advancement: First Findings Reported in Survey on Faculty Careers
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Neurology: Glial Cells Critical for Peripheral Nervous System Health
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Publishing: Online Journal Opens Access to Scientific Literature
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Resources: Harvard Wins $10 M to Build Chemical Libraries, Techniques
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In Mice, Method Multiplies Stem Cells After Marrow Transplant
Brain May Build Memories in Three Stages
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Proceedings of the HMS Faculty Council
CDC Grant Launches HSPH Bioterror Program
National Exhibit Honors Women Physicians
Milestone Series to Explore Molecular Sensing
Honors and Advances
News Brief
In Memoriam:
Lawrence Daltroy
Brina Sheeman Shackelford
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 Finding a Good Way to Give Bad News
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 Behind the White Coat: Depression in Medical School
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Front
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BULLETIN
Proceedings of the HMS Faculty Council
At the Sept. 10 Faculty Council meeting, Joseph Martin, dean of the Faculty of Medicine, welcomed members to the first meeting of the academic year.
Credit on Multi-authored Papers
David G. Nathan, the Robert A. Stranahan distinguished professor of pediatrics, and chair of the Committee on Credit and Responsibility for Individual Authors of Multi-authored Papers, told the council that the goal of the committee was to find reasonable ways to recognize middle authors, who rarely get credit in the Harvard evaluation system for purposes of academic promotion.
The committee made three main recommendations:
- Statement on collaboration. A formal statement should be made in the "Purple Book," HMS's System of Titles and Appointments, Criteria and Procedures for Making Permanent, Term and Annual Appointments, on the value of collaboration. This statement should say, "committees that evaluate candidates for promotion must carefully evaluate the bibliography and search for evidence of productive collaboration that has led to important publications without limiting themselves to the information that such committees can gather from the order of authorship in the candidates' publications."
- Self-reporting. Promotions committees should rely in part on self-reporting by individual candidates with respect to roles served on research projects on which they have productively collaborated.
- Confirmation of self-reporting. Each candidate's promotion proposal that claims a productive collaboration must be accompanied by substantiation of his or her contributions by an individual in a position to do so, presumably the senior author (or guarantor). The validating information should be solicited by the department head, not the candidate.
The committee also recommended that each paper submitted to a journal or promotion include a statement that briefly describes the contribution of each author on the publication and that the senior author (or guarantor) may designate that a paper has as many as three lead authors, each of whom has made substantial contributions to the design and analysis of the work and the writing of the manuscript. Each lead author is equally responsible for the integrity of all the data in the manuscript, the accuracy of analysis, and the conclusions. These recommendations cannot be enforced by Harvard, but instead depend upon the cooperation of the journals. If a journal will not permit these addenda, then the senior author should attempt to submit it online or at the very least retain a copy of the statement in his or her files. Additionally, the committee recommended that electronic versions of papers with such credits be considered by promotions committees.
The committee also recommended the Purple Book designate that the department head's promotion package letter specifically describe collaborative as well as independent research projects; that a section on multi-authored papers be added referring to the recommendations in this report; and that a new section, II F, be added to the candidate's CV. This section should be titled "Report of Collaborative Activities."
Medical Education Reform
Malcolm Cox, dean for medical education, speaking on behalf of the Task Force for a New Curriculum, which was cochaired by Philip Leder and George Thibault, told the council that the curriculum task force had been charged with making recommendations on the need for curriculum reform (particularly in the clinical years), the scope of reform, the organization of reform (if it is necessary), and the resources needed to bring it about.
The task force acknowledged that patient through-put has accelerated massively over the past 15 years, and as a result, current hospital inpatient services no longer represent the full spectrum of illness or patient experience. The increased pace is less and less hospitable to the educational needs of students who are often marginalized as members of inpatient teams.
The task force recommended that the entire curriculum be reviewed and revised as necessary to achieve a series of goals that focus on curriculum and address infrastructural issues (including appropriate rewards for teaching). To evaluate and act upon the recommendations, a system of governance and of working groups will be put into place. Under governance, an executive committee comprising the dean and senior School and hospital leadership will be established. In addition, a steering committee, chaired by Cox, will be formed and will include the chairs of the working groups, charged with examining various aspects of curriculum reform. Currently, the working groups envisioned will focus on curriculum blueprint and themes, integration of science and clinical medicine, new models for clinical education, faculty-student relations, admission requirements, pedagogy, assessment, educational technology, faculty compensation, faculty promotion and evaluation of teaching, and faculty development. The aim is to have a final report ready in spring 2004.
The meeting concluded with the dean's description of planning for the new Department of Systems Biology and the reorganization of the Dean's Office.
CDC Grant Launches HSPH Bioterror Program
A $250,000 start-up grant from the Centers for Disease Control and Prevention (CDC) has been awarded to Harvard's School of Public Health and Kennedy School of Government to establish the National Preparedness Leadership Academy (NPLA). The academy aims to educate senior government officials on ways to improve the web of people, organizations, and resources who respond to a bioterrorist attack or public health emergency. Leonard Marcus, HSPH faculty member and codirector of the NPLA, said the academy aims to "develop a curriculum and training program that will help officials at all levels of government to better understand the challenges of reaching the national imperative of complete preparedness."
National Exhibit Honors Women Physicians

In a tribute to the achievements of women physicians, the National Library of Medicine opened an exhibit, "Changing the Face of Medicine: Celebrating America's Women Physicians," on Oct. 14 at the library's NIH headquarters in Bethesda, Md. Complementing the display is an interactive website. Of the 338 physicians honored, 22 are HMS alumnae and many more are otherwise associated with the School. This list includes, but is not limited to Tenley Albright (left), Mary Ellen Avery, JudyAnn Bigby, Elizabeth Hay, JoAnn Manson, Barbara McNeil, Deborah Prothrow-Stith (right), Joan Reede, Lynne Reid, and Eleanor Shore. Saluting these doctors, the library says, "They overcame prejudice and discrimination to create and broaden opportunities within the profession. Persistence, ingenuity, and ability enabled them to advance in all areas of science and medicine." The exhibit runs through April 2, 2005.
Milestone Series to Explore Molecular Sensing
On Dec. 4, the third in a series of symposia honoring the 100th anniversary of the Longwood Quadrangle groundbreaking will be held in the new research building from 8:30 a.m. to 12:30 p.m. The panel discussion, "Molecular Sensing in the Brain," will feature Eric Kandel, University Professor, Columbia University, and HHMI investigator; Carla Shatz, the Nathan Marsh Pusey professor of neurobiology, HMS; Cori Bargmann, professor of anatomy, University of California, San Francisco, and HHMI investigator; David Corey, professor of neurobiology, HMS, and HHMI investigator; John Assad, assistant professor of neurobiology, HMS; and Connie Cepko, professor of genetics, HMS, and HHMI investigator (moderator). All events in the series require a Web-based RSVP. To register or to get more information about this and upcoming symposia in the Milestone series, visit www.hms.harvard.edu/milestone.
Honors and Advances
Pediatric heath care provider Nemours has awarded Lucian Leape, HSPH adjunct professor of health policy in the Department of Health Policy and Management, the 2003 Alfred I. DuPont Award for Excellence in Children's Health Care. Leape, a former pediatric surgeon, received the $50,000 prize for his leadership on medical error prevention. He has donated the award to the Boston Minuteman Council of the Boy Scouts of America, which supports programs in diversity training and encourages inner city youths to join scouting.
England's Royal College of Surgeons elected James Herndon an honorary fellow. Herndon is the Harris professor of orthopedic surgery and chairman of the Partners Department of Orthopedic Surgery at Massachusetts General Hospital.
Nancy Turnbull, HSPH lecturer on health policy in the Department of Health Policy and Management, has been named executive director of the new Massachusetts Medicaid Policy Institute. The institute, founded by Blue Cross Blue Shield of Massachusetts, provides nonpartisan research, information, and analysis of the Medicaid program in the state.
The American Liver Foundation has awarded Karen McCowen, HMS assistant professor at Beth Israel Deaconess Medical Center, the Congressman John Joseph Moakley On-going Liver Scholar Award for her project titled "Fatty Acid Metabolism in Malabsorption."
The National Quality Forum and the Joint Commission on Accreditation of Healthcare Organizations awarded Jeffrey Cooper, director of biomedical engineering for Partners HealthCare System and HMS associate professor of anesthesiology at Massachusetts General Hospital, the John M. Eisenberg Award for Lifetime Achievement in Patient Safety. In 1972 Cooper led seminal studies on human error in anesthesia. He also helped design the Boston Anesthesia System, one of the first pieces of microprocessor-based medical equipment.
News Brief
Katie Couric, longtime co-anchor of NBC's Today, has been awarded HSPH's highest honor, the Julius B. Richmond Award, for her work on the prevention of colon cancer. In March 2000, Couric aired a series on Today, "Confronting Colon Cancer," to raise public awareness about the nature of the disease and prevention strategies. She also launched the National Colorectal Cancer Research Alliance with Lilly Tartikoff and the Entertainment Industry Foundation. The award takes it name from former U.S. Surgeon General Julius Richmond.
In Memoriam
Lawren Daltroy, HMS associate professor of medicine at Brigham and Women's Hospital and HSPH associate professor in the Department of Society, Human Development, and Health died on Sept. 22 following a recurrence of melanoma. He was 54.
Daltroy received a bachelor's degree in history in 1971 and a master's in public health in 1974 from the University of Michigan. He went on to earn a doctorate in health education from the Johns Hopkins School of Hygiene and Public Health in 1982. He became director of educational research of the Robert Brigham Arthritis and Musculoskeletal Clinical Research Center at BWH, and since 1988 was its associate director.
Daltroy was an internationally recognized authority on health education and physician-patient communication. He conducted novel research on patient self-medication in hospitals, spousal support for cardiac patients, and work-site health education. He did seminal work on helping patients with arthritis communicate effectively with their health care providers to achieve better health outcomes.
In honor of his achievements, Daltroy was recognized as a Distinguished Scholar by the National Arthritis Foundation. He was a consultant to the National Arthritis Advisory Board, the National Heart, Lung, and Blood Institute, and the Arthritis Foundation, among other organizations.
Also a distinguished teacher, he mentored generations of graduate students and physicians. Among his many teaching awards was the prestigious Roger L. Nichols Excellence in Teaching Award for 2003 from HSPH.
Daltroy is survived by his wife, Mary Ni; his daughters, Susan and Alison Daltroy and Jenny Ni; his parents, Frederick and Louise D'Altroy; and his brother, Terence D'Altroy.
The family suggests that remembrances be made in the form of gifts to the Lawren H. Daltroy Fellowship, endowed in his honor. Contributions can be sent to the Research and Education Foundation of the American College of Rheumatology, 1800 Century Place, Suite 250, Atlanta, GA 30345. (Photo courtesy of Harvard School of Public Health)
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The faculty and staff of HMS mourn the loss of beloved fifth-year graduate student Brina Sheeman Shackelford, 27, who died on Oct. 12 after a car accident. Her friends and colleagues in the Division of Medical Sciences and in David Pellman's lab at the Dana-Farber Cancer Institute knew her as a bright, vivacious, and compassionate woman and a wonderfully promising young scientist. Her family requests that donations in her memory be made to Graduate Program, Harvard Medical School, Brina Sheeman Shackelford Memorial Fund, 25 Shattuck Street, Boston, MA 02115.
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