April 22, 2005
Immunology
Body Builds Defense
Against Pneumococcus
Without Antibodies
At the Podium
Race Complicates Views on Genes And Medicine
Neurosurgery
Aggressive Surgery for Low-grade Brain Tumor May Lengthen Life
Medical Education
Website Opened to Support Cross-cultural Care

Entire Fruit Fly Genome Plumbed for Pathway Participants
Molecular Teams Decide Nerve Cell Fates
Blue Light Puts Red Gums in the Pink

Grant to Improve Managed Care Treatment of Drug Abuse
New Faculty Appointments to Full Professor
Plasmid Repository Supports Research in Genomics
Longwood Symphony Gives Benefit for Homeless Patients
Innovator Award
Goes to HSPH Cancer Researcher
Honors and Advances
News Brief: AMA Foundation 2005 Leadership Awards
Name of Countway’s Rare Books Department Is History
Nine Students from LMA Selected as Schweitzer Fellows
HST Student Research
Reaches for the Stars

Reproductive Health
Problems on the Wards
Front Page
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BULLETIN
Grant to Improve Managed Care Treatment of Drug Abuse
The Brandeis/Harvard Center on Managed Care and Drug Abuse Treatment has
received $6.3 million from the National Institute on Drug Abuse to develop
mechanisms for improving drug abuse treatment services for managed care patients.
The Brandeis/Harvard center, a collaboration between Brandeis University’s
Center for Behavioral Health and the HMS Department of Health Care Policy,
will use the money to fund three research projects aimed at improving these
patients’ access to high-quality substance abuse treatment. The projects
will investigate how organizational management, financing, and payment within
managed care can be improved to benefit substance abusers seeking treatment. “We’re
focusing on how to improve the system to better serve this group of patients,” explained
Richard Frank, the co–principal investigator and the Margaret T. Morris
professor of health care policy at HMS.
Young Scientists Compete for Regional Honors

Photo by Steve Gilbert
John Zeqi Luo displays his first-prize plaque, flanked by Changiz Geula
(left), HMS associate professor of medicine (neuroscience) at Beth Israel
Deaconess
Medical Center, and Lynne Reid, the S. Burt Wolbach distinguished professor
of pathology at HMS and Children’s Hospital Boston. Luo won the award
at the Junior Science and Humanities Symposium (JSHS) on April 1 and 2 for
his presentation, titled “American Ginseng Improving Pancreatic Beta
Cell Function May Result from the Alteration of Metabolism, Cell Proliferation,
Differentiation, and Apoptosis Gene Expression: Microarray Approach.” Luo
received a $1,500 scholarship and will be among five students representing
southern New England at the National Symposium in San Diego. The Boston
symposium was sponsored by the HMS Minority Faculty Development Program
and gave participants
the opportunity to tour laboratories of leading researchers and gain exposure
to various clinical settings at the Harvard teaching hospitals.
New Faculty Appointments to Full Professor
The following faculty members were appointed in March.
Charles Nelson
Professor of Pediatrics
Children’s Hospital Boston
Nelson’s research interests are concerned with developmental
cognitive neuroscience, an interdisciplinary field involving developmental
neuroscience and developmental psychology. His specific interests
are the effects of early experience on brain and behavioral development,
particularly as it influences memory and the ability to recognize
faces. Nelson studies both typically developing children and children
at risk for neurodevelopmental disorders, employing behavioral,
electrophysiological, and metabolic tools in his research.
Andrew Luster
Professor of Medicine
Massachusetts General Hospital
Luster’s research focuses on the control of leukocyte trafficking
during inflammatory and immune responses by chemokines and chemoattractant
receptors. He has been studying the biology and pathobiology of
this superfamily of chemotactic cytokines for over 20 years, beginning
with his discovery of one of the very first chemokines as an MD–PhD
student. Luster studies how chemokines and chemoattractant receptors
orchestrate the precise movement of leukocytes necessary to generate
and deliver a protective immune response, how this system of chemoattractants
controls the trafficking of leukocytes in disease, and how this
information can be translated into new therapies for inflammatory
diseases. Luster is chief of the Division of Rheumatology, Allergy,
and Immunology and director of the Center for Immunology and Inflammatory
Diseases at MGH. He is also a member of the immunology graduate
program at HMS.
Plasmid Repository
Supports Research in Genomics
The DF/HCC DNA Resource Core is offering new benefits to DF/HCC
investigators through its plasmid repository and distribution service.
The plasmid repository was created in response to a need for plasmid
storage and distribution services due to the increase in genome-scale
research efforts. The service provides archival storage of glycerol
stocks in a state-of-the-art automated freezer; automated tracking,
robotic arraying, and other measures designed to ensure clone viability;
scientific support for transfer of clones and information from
the lab; and storage for more than 80,000 individual samples. Its
collection currently includes over 30,000 clones, including sequence-verified
cDNAs from humans and other organisms, expression vectors, and
more. For further information on the Resource Core’s services,
please visit http://dnaseq.med.harvard.edu.
Longwood Symphony Gives Benefit for Homeless Patients
The Longwood Symphony Orchestra, most of whose members are health
care workers, will be performing a benefit concert on May 14 at
8 p.m. Proceeds will go toward the Boston Health Care for the Homeless
Program, which cares for homeless patients at 68 sites in greater
Boston. Tickets for the concert cost $25 for adults and $15 for
students and seniors. The concert will be held in Jordan Hall at
the New England Conservatory. For more information, see www.longwoodsymphony.org.
Innovator Award Goes to HSPH
Cancer Researcher
Dimitrios Trichopoulos, the Vincent L. Gregory professor of cancer
prevention at HSPH, was awarded an “Innovator Award” by
the U.S. Department of Defense. The five-year, $5.8 million grant
is given to individuals who have a “history of visionary
scholarship, leadership, and creativity,” and will fund Trichopoulos’s
research on fetal and early-life factors associated with adult
breast cancer. As part of this research, Trichopoulos and colleagues
in the United States, Sweden, and Greece will undertake a series
of five complementary studies designed to investigate links between
early-life exposures, mammary gland stem cells, mammary gland mass,
and adult breast cancer.
Honors and Advances
Mark T. Keating, Howard Hughes investigator and
HMS professor of cell biology and pediatrics at Children’s
Hospital Boston, was selected to receive the 15th annual Bristol–Myers
Squibb Freedom to Discover Award for Distinguished Achievement
in Cardiovascular Research. Keating was honored for discovering
the first arrythmia genes and demonstrating that these genes encode
the ion channels that regulate the excitation and contraction of
the heart. Keating will be officially presented with the $50,000
award and a silver commemorative medallion at a dinner in his honor
on October 19.
The Graduate Student Council presented Stephen Soumerai with
a 2005 Everett Mendelsohn Excellence in Mentoring Award at an event
held in the Faculty Club on March 24. The award is given annually
to three Harvard professors who demonstrate exceptional care for
the lives and work of graduate students. Soumerai, an HMS professor
of ambulatory care and prevention and health policy, was honored
for his attention to the role stress plays in students’ lives.
News Brief
Roy Hamilton and Jacqueline Onyejekwe have both
received American Medical Association Foundation 2005 Leadership
Awards. The prizes provide medical students, residents, fellows,
and young physicians with training to develop skills as future
leaders. Hamilton graduated from HMS in 2001 and is currently working
as the educational director for Pipeline, a mentoring program for
minority medical students at the University of Pennsylvania. Onyejekwe
is a research fellow in social medicine and a Commonwealth Fund
fellow in minority health policy at HMS. They were presented with
the awards at a ceremony on March 13.
Name of Countway’s Rare Books Department Is History
The Francis
A. Countway Library’s Rare Books and Special Collections
Department changed its name to the Center for the History of Medicine
on April 1. The center will promote the study of the history of
medicine to achieve a better understanding of the complex interaction
between medicine and society. It will carry out its mission by
adding to, preserving, and making accessible the Countway’s
extensive historical library and museum collections and by sponsoring
programs that demonstrate their value and usefulness.
Nine Students from LMA Selected as Schweitzer Fellows
Nine HMS and HSPH students have been selected 2005–2006
Boston Schweitzer Fellows. The fellowship, founded in honor of
Albert Schweitzer, requires fellows to commit to a year of service
with a community agency and devote more than 200 hours to local
communities lacking access to adequate health services. Once fellows
have completed their year of service, they join a network of more
than 1,200 Fellows for Life. The new fellows include Olufemi
Adegoke, Deborah Cook, Ana Diaz, and Raymond Tsai from
HSPH and Surbhi Grover, Celeste Lopez, Ashley Morris, Zachary Morris, and Stacy
Truta from HMS. Their projects include helping female inmates create a health
column in their prison newspaper, advocating for immigrant health
and health education, and creating a mentoring program for boys
living in a battered women’s shelter. For more information
on the program, visit
www.schweitzerfellowship.org.
HST Student Research Reaches for the Stars
 Photo by Liza Green, HMS Media Services |
Christopher Carr (left) describes the International Development
Initiative at the Harvard–MIT Health Sciences and Technology Forum on March
31 in the NRB. The initiative is an MIT program that uses technology to improve
the daily functions of life in developing nations. Innovations have included
a solar-based water disinfection system and development of charcoal that burns
more cleanly and has a higher energy density. Carr also presented a less down-to-earth
project, demonstrating that oxygen is used more efficiently when running in a
space suit than when walking. More than 75 HST students presented their research
during the poster session.
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