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Genomics
Epigenetics
Sleep Medicine Health Care Policy Bacteria May Be Early Signal of Oral Cancer Step Taken Toward $1,000 Personal Genome Fat Cell Protein Seen to Cause Insulin Resistance Department Chair, Assistant Dean Named at HSPH School Welcomes Incoming Students New Full and Endowed Professorships AIDS Vaccine Program Gains $19m Grant Surgeon-Journalist Plies Both Trades in Iraqi War Zone |
BULLETIN
Department Chair, Assistant Dean Named at HSPH
Nancy Turnbull (bottom), HSPH senior lecturer on health policy, was named assistant dean for educational programs, a new position at the School. In this role, Turnbull aims to better integrate public health practice into the classroom, improve case-based learning, and introduce new approaches for student advising and mentoring. She will also develop alternative scheduling to minimize course conflicts for students and different educational formats, including online learning. “HSPH already offers top-notch curricula, but we want to ensure that the School is always a leading, international educator in public health,” said Turnbull.
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Melody Russell (left) and Kara Wong (foreground, right) were among the 165 incoming MD and HSDM students who received their white coats on Sept. 1 at the Schools’ welcoming ceremony for first-years. Women make up 52 percent of the incoming class, and 22 percent of the first-years are underrepresented minorities. At the Division of Medical Sciences’ incoming student gathering on Sept. 9, program heads discussed the value of basic and fundamental research with the 90 new students. Thirty-eight of DMS’s first-years are male and 52 are female.
The following faculty members were appointed to a full or named professorship in August.
G. William Dec
Roman W. DeSanctis Professor of Medicine
Massachusetts General Hospital
Dec’s research interests focus on inflammatory diseases of the myocardium,
particularly viral-mediated myocarditis and cardiac allograft rejection.
His clinical and histopathological studies have helped to define the relationship
between myocarditis and dilated cardiomyopathy and to better characterize
the natural history and treatment of these disorders. At MGH, he remains
active in the conduct of clinical trials of novel pharmacological and device-based
heart failure therapies, disease management strategies, and genetic determinants
of recovery from acute onset cardiomyopathy, and he serves as chief of the
hospital’s Cardiology Division.
Craig Gerard
Leila and Irving Perlmutter Professor
Children’s Hospital Boston
Gerard’s research has focused on G protein chemo-attractant receptors,
particularly those for complement anaphylatoxins C3a and C5a and the chemokines.
His work has led to translational research on the pathogenesis of several
diseases, including cystic fibrosis, asthma, rheumatoid arthritis, and HIV/AIDS.
At Children’s, he is director of the Adult Cystic Fibrosis Center and
chief of the Division of Respiratory Diseases.
David Beier
Professor of Medicine
Brigham and Women’s Hospital
Beier’s work has focused on the study of mouse mutations as models
of human disease and development. This has encompassed all aspects of mouse
genetics, including gene mapping, positional cloning, complex trait genetics,
and genomics. His work currently focuses on the use of mutagenesis to generate
models of human birth defects.
Robert Moellering
Shields Warren–Mallinckrodt
Professor of Medicine
Beth Israel Deaconess
Medical Center
Moellering’s research focuses on the mechanisms of action, particularly
mechanisms or resistance to antimicrobial agents. In addition, he and his
colleagues are involved in a number of studies of the relationship between
antimicrobial resistance and virulence in bacteria, including methicillin--resistant
Staphylococcus aureus. He is head of the Department of Medicine at BID.
Kenneth
Bloch
William Thomas Green Morton
Associate Professor of Anesthesia
Associate Professor
of Anesthesiology and Medicine
Massachusetts General Hospital
Bloch’s research focuses on the roles of nitric oxide in the pathogeneses
of cardiopulmonary diseases, especially those associated with left ventricular
dysfunction and acute pulmonary injury. His group also studies the mechanisms
by which mutations in the gene encoding the type II bone morphogenetic protein
receptor cause pulmonary arterial hypertension.
The following faculty members were appointed to a full or named professorship in July.
William Gregory Stevenson
Professor of Medicine
Brigham and Women’s Hospital
Stevenson’s research centers on the diagnosis and treatment of cardiac
arrhythmias. He has developed methods for characterizing areas of abnormal
electrical activity in the heart and eliminating these with catheter ablation
techniques. He is also interested in the prevention of sudden death and
strategies to reduce sudden death in heart failure patients.
Abram Recht
Professor of Radiation Oncology
Beth Israel Deaconess Medical Center
Recht’s research focuses on investigating and improving the results
of local and regional therapy for patients with early-stage breast cancer,
particularly when combined with systemic therapy. He has written, edited,
or co-authored more than 200 publications on the topic. He has also studied
combined-modality approaches for the treatment of gastrointestinal cancers.
Nancy
Tarbell
C.C. Wang Professor
of Radiation Oncology
Massachusetts General Hospital
Tarbell’s clinical research focuses on pediatric cancer treatment
with a special interest in decreasing late effects in cancer survivors.
Her current
collaborative research is directed toward defining the benefit of proton
radiation therapy in childhood brain tumors. She currently serves as the
director of the Pediatric Radiation Oncology Service as well as the director
of the Center for Faculty Development at MGH.
Mark Zeidel
Herrman Ludwig Blumgart
Professor of Medicine
Beth Israel Deaconess
Medical Center
Zeidel’s research focuses on the control of water and sodium
transport across biological membranes. His achievements include defining
the renal
mechanisms of action of atrial natriuretic peptides, developing a molecular
understanding of how barrier membranes block the fluxes of water and other
small molecules, and performing the first successful reconstitution of
aquaporin water channels, which led to a detailed understanding of how
they function
to transport water. Zeidel was also named chairman of medicine at BID on
July 1.
Joseph Loscalzo
Hersey Professsor of the Theory
and Practice of Physic
Brigham and Women’s Hospital
Loscalzo investigates vascular and endothelial biology, with
an emphasis on endothelial function, thrombosis, and oxidant stress.
He has
spent years
researching the role of nitric oxide as an essential endothelial homeostatic
effector and has examined the key determinants of its elaboration and
its oxidative inactivation. Among the molecular and genetic mediators
of oxidant
stress and vascular disease that his group has identified are glucose-6-phosphate
dehydrogenase deficiency, glutathione peroxidase-1 and -3 deficiencies,
and hyperhomocysteinemia, all of which contribute to the development
of vascular
nitric oxide insufficiency. He was named to the Hersey professorship
along with his appointment as chair of BWH’s Department of Medicine.
Jonathan
Borus
Stanley Cobb Professor of Psychiatry
Brigham and Women’s Hospital
Borus is the chair of the Brigham and Women’s/Faulkner Hospitals Department
of Psychiatry and the chief of psychiatry at both hospitals. His work involves
psychiatric education, health and mental health delivery systems, and physicians’ personal
and professional development.
Jules Dienstag
Carl W. Walter Professor of Medicine
Harvard Medical School
Dienstag is a hepatologist whose professional career in the Gastrointestinal
Unit at Massachusetts General Hospital has been devoted to the study
of viral hepatitis. His current research focuses on development of antiviral
therapy
for chronic viral hepatitis, and he is the principal investigator at
MGH
of a national, randomized, controlled trial of protracted antiviral therapy
for patients refractory to treatment for chronic hepatitis C. Between
1998 and 2004, Dienstag was the faculty associate dean for admissions and
chairman
of the Committee on Admissions at HMS. In 2004–2005, he was associate
dean for academic and clinical programs at HMS, and on May 1, was appointed
dean for medical education at HMS and the incumbent of the Walter chair.
Jerrold
Rosenbaum
Stanley Cobb Professor of Psychiatry
Massachusetts General Hospital
Rosenbaum is an authority on mood and anxiety disorders and their pharmacotherapy.
His research contributions include extensive participation in the design
and conduct of clinical trials of new therapies. His work includes the
design and implementation of trials to develop innovative treatments for
major depression,
treatment-resistant depression, and panic disorder; studies of psychopathology
including comorbidity and subtypes; and studies of longitudinal course
and outcomes of these disorders. He has also been involved in ongoing longitudinal
studies of children at risk for anxiety and depression.
Researchers at Beth Israel Deaconess Medical Center and Crucell Holland BV, a Dutch biotechnology company, have been awarded a $19.2 million five-year grant from the National Institutes of Health to develop a novel candidate HIV/AIDS vaccine.
The Integrated Preclinical/Clinical AIDS Vaccine Development program will be headed by Dan Barouch, HMS assistant professor of medicine at BID. Other members of the scientific team include Norman Letvin, HMS professor of medicine at BID, and Raphael Dolin, the dean for academic and clinical programs at HMS and the Maxwell Finland professor of medicine (microbiology and genetics) at Brigham and Women’s Hospital, with Jaap Goudsmit, chief scientific officer of Crucell Holland BV.
• Dennis Kasper, the William Ellery Channing professor of medicine at Brigham and Women’s Hospital, has been selected to chair the new National Science Advisory Board for Biosecurity (NSABB). The NSABB is a 24-member committee created by the U.S. Department of Health and Human Services to recommend strategies for regulating federally conducted or supported biological research that has the potential to be used for harmful purposes..
• Queen Elizabeth II of England has appointed Donald Berwick, HMS clinical professor of pediatrics and health care policy at Children’s Hospital Boston, an honorary Knight Commander, Order of the British Empire. Berwick was recognized for his “distinguished service to health care improvement in Britain’s National Health Service,” including his work on the modernization plan for the UK health care system and on the National Patient Safety Agency. “We are deeply grateful for Dr. Berwick’s invaluable contributions to improving Britain’s National Health Service, and with it the health of people throughout the UK,” said British Consul-General John Rankin. The knighthood is honorary because Berwick is not a British citizen.
• Jane M. Murphy, HMS professor of psychiatry at Massachusetts General Hospital and HSPH professor of epidemiology, was presented with the Hoch Award at the March 2005 Annual Meeting of the American Psychopathologic Association. The award is given to an investigator who has made seminal contributions to psychiatric research. At the meeting, Murphy gave a presentation on her long-term epidemiologic study of psychiatric disorders in a general population and provided a history of psychosocial research focused on the etiology of psychiatric disorders.